Endocrine Abstracts

Background: Impaired insulin and glucose levels are implicated in the etiology of cardiovascular disease, however, their influence on the formation and composition of atherosclerotic plaque remains unclear.Purpose: To investigate the association between fasting serum insulin and glucose levels with atherosclerotic plaque composition in the carotid artery.Methods: In 1740 participants (mean age 72.9 years, 46% women, 14.4% diabetes ...

IntroductionIndividuals with type 2 diabetes mellitus (T2DM) are at an increased risk of developing fractures, despite higher mean BMI and BMD. Recently, clinically relevant sub-groups of T2DM have been characterised using biomarkers of glycemic metabolism.AimCharacterise T2DM sub-groups in a population-based setting and test for differences in fracture risk.Methods<p class="abstext...